What Is Microdosing LSD?

In recent years, a new form of substance abuse is becoming increasingly common among stay-at-home moms and CEOs alike: microdosing LSD. Microdosing refers to taking a small fraction of what is considered a recreational dose of LSD or other Hallucinogen (like Psilocybin Mushrooms, also known as Magic Mushrooms). Microdosing certain Psychedelic drugs can reportedly improve mood, induce physical and mental stimulation, and encourage creative thinking. Emerging studies support the notion that Hallucinogenic drugs, taken in small doses or under the supervision and guidance of a medical professional, can be used to treat mental health issues such as depression, anxiety, and PTSD. However, taking consistent and frequent doses of any drug, especially one as potent as LSD, is by no means safe for all individuals and may put certain people at a high risk for developing addiction.

Given many Hallucinogens’ status as Schedule I drugs, it is difficult to conduct FDA-approved scientific studies. Moreover, most microdosing studies rely on reporting and statistics provided by self-proclaimed “microdosers” who would likely have a positive bias regarding the practice. Consequently, legitimate claims made regarding mental health treatment with Psychedelics remain rare.

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Microdosing Origins: Shared Experiences Online

Microdosing LSD and other Hallucinogens initially gained popularity among drug users sharing their experiences on the internet. Practitioners used online community forums (such as Reddit) and Psychedelic information sites’ message boards (like Erowid) to boast about the “benefits” of microdosing.

While both LSD and Magic Mushrooms are illegal on the federal level in the US and in many other countries, more and more people are beginning to claim that small amounts make them feel more focused, creative, and productive. Testimonies of individual experiences with microdosing can be found from people of nearly every demographic: young tech industry employees, middle-aged parents with children, and even high-ranking corporate executives from prominent companies.

However, these testimonials don’t come from medical or psychiatric professionals. LSD and other Psychedelics are dangerous and illegal; their use can cause serious medical, social, and legal complications.

The Changing Stigma Of Hallucinogen Use

These claims online, despite having no scientific backing, quickly turned the practice from niche hobby to nationwide phenomenon. Yet, despite the claimed benefits, microdosing remains a form of substance abuse.

Notably, many users reported first trying microdosing as a substitute for Adderall (a Stimulant prescribed to treat ADHD). Adderall is also referred to as a “study drug” or “smart drug” by many college students and young professionals who misuse it, either by taking it without a prescription or by taking it in excessive quantities. Because of the perceived positive effects on work or school performance, many people who don’t consider themselves typical drug users may be attracted to microdosing LSD.

When it comes to the classic perception of Psychedelics users, the image that typically comes to mind is one of long-haired and colorfully dressed hippies attending Woodstock. Few would imagine that tech moguls and software geniuses in Silicon Valley have been using these drugs for years, citing their alleged performance enhancing properties. The microdosing trend in Silicon Valley has even been the subject of articles in mainstream and notable media sources including Rolling Stone and Forbes. Catchy titles garner ever more attention from the media and readers, describing LSD as “The Hot New Business Trip.”

Are things so dire in the workplace that some persons are now turning to micro doses of psychedelics in order to reach new heights in creativity?

- Robert Glatter, contributor to Forbes, 2019

While some writers took on a positive tone in regard to the trend, many medical and psychiatric professionals expressed concern at the lengths people would go to in order to enhance their productivity and creativity in today’s competitive job market.

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Microdosing And Mental Illness

There is an emerging body of research looking into the possible benefits of Psychedelic drugs in treating mental illnesses such as depression, anxiety, PTSD, and even addiction to other substances. Last year, 2 studies found that Psilocybin could alleviate symptoms of otherwise treatment-resistant depression. These studies showed no evidence of the side-effects seen with conventional Antidepressants, such as mood swings or apathy. A similar study of Ayahuasca, an Amazonian plant mixture with Psychedelic qualities, had promising results and could be “a safe and promising treatment” for both depression and alcohol use disorder. Another study specifically examining the effects of microdosing LSD, Psilocybin, and Mescaline found that participants reported heightened levels of creativity, focus, happiness, and productiveness. While long-term results showed a decrease in depression and anxiety symptoms, researchers also found an increase in neuroticism and unpleasant emotions in some participants.

It’s exciting, but the potentially adverse changes in neuronal structure and metabolism that we observe emphasize the need for additional studies.

- David Olson, Ph.D.

Despite the results of these studies, there is still not enough peer-reviewed and validated research on the topic, making it dangerous for people to try microdosing on their own. Not only is it dangerous to consume any drug without the guidance and supervision of a medical professional, but the potential side effects are ultimately unknown. Additionally, the practice of mixing substances such as LSD or Psilocybin with Antidepressants can be dangerous and even lethal. There are numerous cases where the combination of Hallucinogens and Antidepressants has resulted in the development of serotonin syndrome and other, potentially fatal health issues. Lithium (a medication used in cases of treatment-resistant depression), in particular, is known to put people into comatose states or induce seizures when taken in combination with LSD.

Dangers Of Microdosing

There is a common misconception that Hallucinogenic drugs are relatively safe because they’re not as physically addictive as other illicit drugs, such as Benzodiazepines and Opioids. However, while Hallucinogens typically don’t produce severe symptoms of physiological addiction, it is very possible to become psychologically addicted to any drug of abuse. Furthermore, microdosing can induce feelings of euphoria, heightened awareness, and general well-being. The neurotransmitters responsible for creating such a positive association may put certain people at risk of developing a psychological addiction. Fundamentally, addiction is harmful because, as a chronic disease, it will grow and take prevalence over other aspects of one’s life.

Another concern with microdosing is that many of the potential harms and side effects are generally unknown. Many of the aforementioned studies are conducted by systematically tracking the experiences of people who are already microdosing using an anonymous online system. This makes it more difficult to control the substance use of participants and get accurate results. Instead, results rely on the accuracy and honesty of participants’ reports.

Featured Centers Offering Treatment for LSD

Furthermore, some drugs with Hallucinogenic properties pose potential risks when microdosing due to other characteristics that many classic Hallucinogens (such as MDMA) don’t have. MDMA, commonly sold on the street as Ecstasy or Molly, is typically associated with Hallucinogens because it can produce hallucinations when taken in certain quantities. However, most classify Ecstasy as a Stimulant due to its Amphetamine-like effects. Stimulants, including Ecstasy, increase a person’s risk for developing various heart diseases and death. This is due to MDMA’s activation of the 5-HT2B receptor, a serotonin receptor, which is also activated by LSD and Psilocybin Mushrooms.

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Taking any illicit substance is dangerous. Given the illegality of LSD and other Hallucinogens, there is a high potential for dealers to lace them with other drugs like Fentanyl, Ketamine, or Meth. These adulterants are not only highly addictive, but may cause a fatal overdose.

In addition to these dangers, microdosing exposes users to consistent doses of a potent drug that activates a given area of the brain repeatedly — as opposed to the less-frequent use typically associated with “tripping.” This only increases the risk of developing an addiction or dependency. If you or a loved one is struggling with an addiction, contact a treatment provider today to discuss treatment options.

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Natalie Hoeg

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  • Natalie is currently studying political science, philosophy, and sociology at Stetson University and is also a member of the university's Honors Program. Looking to pursue a career in writing and research, she aspires to go on to earn her Ph.D. so that she can educate fellow inquisitive spirits with a passion for learning. When provided with the opportunity to write for Recovery Worldwide, Natalie has found a passion in helping educate the public about substance abuse and help those battling addiction.

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Reviewed by Certified Addiction Professional:

David Hampton

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  • A survivor of addiction himself, David Hampton is a Certified Professional Recovery Coach (CPRC) and a member of the National Association of Alcohol and Drug Abuse Counselors (NAADAC).

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