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Alcohol And Antidepressants

Combining alcohol with antidepressants has numerous side effects, some of which can be fatal.

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Mixing Alcohol And Antidepressants

Alcohol is classified as a depressant as it depresses nervous systems in our body like heart rate, blood pressure, and respiration. Combining alcohol with antidepressants can be dangerous and even potentially fatal. It is strongly discouraged as alcohol and some antidepressants lead to drowsiness and decreased alertness. Results can create challenges on the job or at home, health issues, and other safety concerns.

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The combination of alcohol and antidepressants can be very complicated if someone is drinking, binge drinking, heavy drinking, or has an alcohol use disorder before taking antidepressants. Furthermore, if someone decides to stop taking drugs for depression and starts drinking alcohol for symptom management instead, he or she can worsen their symptoms of depression.

The Effects Of Combining Alcohol With Antidepressants

Antidepressant classifications such as MAOIs combined with alcohol can result in higher than average blood pressure or a fatal or non-fatal stroke. Other antidepressants combined with alcohol can bring about feelings of drowsiness, dizziness, impaired driving or performing with heavy machinery, and difficulties focusing and concentrating. Unfortunately, people have died combining antidepressants with alcohol, the mixture can lead to suicidal thoughts, plans, or attempts.

If someone who is combining alcohol with antidepressants stops taking their antidepressants, and begins relying on alcohol alone to self medicate, they may increase their alcohol consumption and develop an alcohol use disorder. Combine this with them having a history of depression, and there could be an increased risk of:

  • Alcohol abuse
  • Liver cirrhosis
  • End stage alcoholism
  • Miscarriage 
  • Liver damage
  • Anxiety
  • Feelings of hopelessness, worthlessness, and emptiness
  • Suicidal thoughts

Alcohol may increase the side effects of some antidepressant medications and vice versa. Liver damage from liver toxicity can occur as alcohol and some medications are both metabolized and processed by the liver causing it to work overtime. Drinking moderately or heavily can cause negative effects on other organs  like the brain, resulting in impairments with cognition and brain function.

Pregnancy, Alcohol, And Antidepressants

Drinking alcohol while pregnant is already risky; however, taking antidepressants does not have any known risks toward the unborn child, with the exception of Paxil. Most of the antidepressants do not get transferred through breast milk. Nevertheless, when alcohol gets thrown into the equation, risks like Fetal Alcohol Spectrum Disorder (FASD), Fetal Alcohol Syndrome (FAS), fetal heart defect, poor brain function, abnormalities, and alcohol dependence become possibilities.

An expecting mother is putting both herself and her unborn child at risk for the dangers associated with drinking. For example, a mother who drinks can develop a tolerance to alcohol. Secondly, she may accidentally combine alcohol with other medications prescribed for pregnancy that can have an impact on the unborn child. In the case of FASD and FAS, the child may have a smaller than average sized head, learning disabilities, and other developmental challenges. Fortunately, there is help available specific for neonatal care. Medical treatment professionals can detect substance abuse and risks associated with problem drinking or medications that can impact the mother and unborn child.

Types Of Antidepressants

Antidepressants are drugs that treat symptoms of depression, and are 1 of the 3 most commonly used drug classes in the U.S. A Centers for Disease Control and Prevention (CDC) report cites an increase in antidepressant use from 1999 to 2014. During 2011 to 2014, there was a reported 12.7% of people 12 years old and older using antidepressants. Women were twice as likely to use antidepressants compared to male counterparts. Antidepressants fall into 2 main categories: Selective Serotonin Reuptake Inhibitors (SSRIs) or Monoamine Oxidase Inhibitors (MAOIs). However, there are other types of antidepressants available such as:

  • Dopamine Reuptake Blocker
  • Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)
  • Tricyclic antidepressants (TCAs)
  • Tetracyclic antidepressants
  • 5-HT1A receptor antagonist
  • 5-HT2 receptor antagonist
  • 5-HT3 receptor antagonist
  • Noradrenergic antagonist

Selective Serotonin Reuptake Inhibitors (SSRIs) also treat Obsessive Compulsive Disorders (OCD), anxiety, and bulimia. MAOIs also treat Parkinson’s disease.

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How Antidepressants Work

Some depression is related to having low levels of serotonin in the brain. Serotonin, also known as “the feel good chemical,” is a neurotransmitter in the brain responsible for a sense of well-being. Selective Serotonin Reuptake Inhibitors (SSRI) like Paxil, Prozac, Zoloft, and Lexapro are a class of antidepressants that work by increasing levels of serotonin in the brain. Classifications of drugs like SSRIs and MAOIs are highly effective in reducing symptoms associated with depressive episodes with mild to moderate side effects.

These medications balance neurotransmitters in the brain, leading to better moods, improved quality of sleep, ability to focus, and increased appetite, energy, and motivation. Some antidepressants like Cymbalta can counter nerve pain that comes with fibromyalgia, while other antidepressants can relieve migraines. In some cases, some of these drugs can reduce physical pain. Pain relief can be an extremely helpful aid as depression can worsen physical pain, and pain can worsen depression. The intention of antidepressants is to help someone improve their symptoms of depression, eliminate bodily pain, and help them live a happier life.

Explore Your Treatment Options Today

There are many risks associated with combining alcohol and antidepressants, however, there is help available if needed. Alcohol changes the brains’ chemistry, and quitting cold turkey produces uncomfortable side effects and can even be potentially fatal if you are physically dependent on alcohol. You don’t have to heal alone. Contact a qualified treatment provider to explore available treatment options risk-free.


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